Result card

  • SAF12: Is there evidence that harms increase or decrease in different organizational settings?
English

Is there evidence that harms increase or decrease in different organizational settings?

Authors: Agnes Männik, Irena Guzina, Petra Jandova, Leonor Varela Lema, Gerardo Atienza Merino

Internal reviewers: Matthias Schwenkglenks, Ingrid Wilbacher

The domain literature search was used.

Only two organisational factors (dietary and medication restrictions, cooling measures) were considered to be potentially relevant, which could affect the harms. The accuracy of FOBTs depends upon appropriate performance and interpretation of the test and the interpretation of FOBTs may be problematic when they are done by inexperienced personnel (see SAF7).

In order to reduce the probability of a false positive result, dietary restrictions are usually recommended when guaiac-based tests are used. FIT tests have no dietary or medication restrictions {13}.

However, FIT test samples were requested in one study {10} to be kept in the refrigerator at home and brought back to clinic using cooling bags.

Important
Completely
Männik A et al. Result Card SAF12 In: Männik A et al. Safety In: Jefferson T, Cerbo M, Vicari N [eds.]. Fecal Immunochemical Test (FIT ) versus guaiac-based fecal occult blood test (FOBT) for colorectal cancer screening [Core HTA], Agenas - Agenzia nazionale per i servizi sanitari regionali; 2014. [cited 21 June 2021]. Available from: http://corehta.info/ViewCover.aspx?id=206

References