Result card

  • TEC7: What material investments are needed to use FIT?
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What material investments are needed to use FIT?

Authors: Mirjana Huic, Eleftheria Karampli, Silvia Florescu, Cristian Vladescu

Internal reviewers: Antonio Migliore, Pernilla Östlund, Frida Mowafi, Daniela d’Angela, Jesus Gonzalez

iFOBTs are around 10-fold more expensive than gFOBT. In an evaluation of three automated analytical iFOB methods in the UK {5}, investments made by a laboratory for use of FIT, include:

-Analytical platforms (automated analysers): The number of analysers required will depend on the laboratory workload; number required in the evaluation for a 5,000 sample per day workload will be 1 for HemSp/MagStream HT; 5 for OC-Sensor/DIANA, and 15 SentiFOB and 1 chemistry analyser for FOB Gold/SENTiFOB. All analysers required routine prentative maintance visits (part of the service contract, annualy, but depend on the workload). All analysers required a 13 amp power suplly and purified water to wash the cuvettes (OC-Sensor/DIANA) or for preparation of wash solutions (all three) and system solution (SentiFOB). All three have RS 232-C serial interface ports.

-Sample collection devices: for OC-Sensor the faecal sample was collected into the OC-Auto sampling bottle 3; for Hem-SP/MagStream HT (MagStream Hem-Sp®) the faecal sample was collected into the NEW HEMTUBE; for the FOB Gold the faecal sample was collected into the FOB Gold tube.

- Refrigerated storage space

- Clinical waste disposal.  iFOBT sample collection tubes required disposal in rigid bins to contain any liquid, which required different procedure and more manual handling.

- End of life disposal: end of life disposal of the products may have financial and/or environmental costs, depending on the regulations in place (e.g. Waste Electrical and Electronic Equipment regulation in the UK).

Huic M et al. Result Card TEC7 In: Huic M et al. Description and technical characteristics of technology In: Jefferson T, Cerbo M, Vicari N [eds.]. Fecal Immunochemical Test (FIT ) versus guaiac-based fecal occult blood test (FOBT) for colorectal cancer screening [Core HTA], Agenas - Agenzia nazionale per i servizi sanitari regionali; 2014. [cited 16 June 2021]. Available from: